The Role Of Fundamental Research And Biotechnology

Resistance to antibiotics is becoming a major problem worldwide. alter this bureau is the fact that few new antibiotics be in the development pipeline, and, indeed, no novel class of antibiotics has been introduced into medical drill in more than 20 years. It is proposed that the solutions to the problem of antibiotic electric foeman will be found only finished key research that will probably use bioengineering as a tool. A variety of novel approaches being utilized in university laboratories and biotechnology companies are outlined. 2 approaches in particular, namely, Synsorbs and recombinant cationic peptide antimicrobials, that have been developed through the Canadian Bacterial Diseases Network, a national research consortium, are discussed. One of the major problems with think of to antibiotic chemotherapy is that, despite the intensifier research that is being conducted by the multibillion-dollar pharmaceutical industry, no novel chemic class of antib iotics has been ascertained in the past 20 years [1]. Indeed, whole latterly introduced antibiotic compounds are permutations (i.e., improved versions) of preexisting compounds.

Thus, a situation whereby bacterium can mutate known resistance mechanisms to fight these improved relatives of earlier antibiotics has been created, and it is not queer for significant resistance to be observed hitherto before design of much(prenominal) antibiotics into the clinic [2]. One global priority must therefore be to encourage the development of novel antimicrobials, which will result in diversification of the weapo ns available in the war against pathogenic b! acteria. twain of the major limitations of this objective are the high cost ($ three hundred one thousand thousand per new chemical entity) of medicate development within pharmaceutical companies and the observation that more of the big multinational companies have actually decreased their activities or eventide ceased to invest in the discovery of new antibiotics [3]. Does...If you want to cut a full essay, order it on our website: OrderCustomPaper.com

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